The legendary investigator Sherlock Holmes does not employ deductive thinking or solve puzzles. He does, however, go on the quest for vampires. Vampire Holmes retells the narrative of Sherlock Holmes and his helper in three-minute segments. When the Metropolitan Police of London covertly engage Holmes and Hudson to investigate vampires, what starts off as a normal detective business takes a turn for the paranormal. Or, at the very least, that's what Holmes would say to everyone who inquired. He and Hudson, in truth, spend the most of their time bickering and failing to settle any cases. This is the story of the guy who was most definitely not London's best detective, as told by his not-so-black demon cat Kira and their terrible rent-hungry landlady.