Koushi Nagumo's life takes a turn for the worst when his father abandons him after their house burns down. Koushi falls on the street after being left to fend for himself, but an eccentric woman called Mineru Wachi takes pity on him and brings him to the female dormitory "Megami-ryou." Mineru, the interim manager, invites Koushi to become Megami-official ryou's dormitory mother after knowing about his condition. The dorm's inmates, however, await him, each with their own zany pranks, such as the androphobic yet kind Atena Saotome, the feminine tomboy Kiriya Senshou, and Mineru herself, whose recklessness has no boundaries when it comes to science. Despite this, Koushi does his best to carry out the responsibilities of his strange new existence!