As long as humans have hearts, there will always be some who suffer. Then something "abnormal" enters their consciousness, causing a bizarre sickness to appear in their body. Most people are unaware of the ailment, which is referred to as a "mystery sickness," yet it does exist. There is a doctor and an apprentice who are fighting an illness that modern medicine cannot cure. Ramune is his name. He acts erratically all the time, is foul-mouthed, and does not even resemble a doctor! When presented with the mystery ailment, however, he is able to immediately find the fundamental cause of his patients' great pain and heal them. And then some...